Psychedelics and Personality Change

Psypost – Personality Changes

Study Paper – Effects of psilocybin on personality, psychiatric symptoms, and values: Exploring mediating effects of the acute psychedelic experience

Psychedelic Mushrooms and the Entourage Effect

Scientists engineered a plant to produce 5 different psychedelics at once

Study Paper – Complete biosynthesis of of psychedelic tryptamines from three kingdoms in plants

Psychedelic Mushrooms and the Entourage Effect

Psilocybin might no be the most active ingredient in magic mushrooms, new research suggests 

Study Paper – Network pharmacology and molecular simulation reveal the entourage effect of psilocybin-producing mushrooms on the brain

DMT Functionality in the Brain

Study Paper – DMT is neither formed nor retained in serotonin terminals in the rat brain

DMT Antidepressant research

Study Paper – A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial

Mapping the phenomenology of 5-MeO-DMT 

Study Paper – Mapping the phenomenology of intranasal 5-MeO-DMT in psychedelic-naïve healthy adults

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks 

A dose of psilocybin, a dash of rabies point to treatment for depression – Cornell Chronicle

Study Paper –Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks 

New research into mushrooms that invoke visions of tiny people

Natural History Museum of Utah

Psilocybin-assisted therapy and psychological flexibility

Study Paper – Psychological flexibility as a mechanism of change in psilocybin-assisted therapy for major depression 

Psilocybin-assisted therapy 5-year follow-up

Depression remission endures 5 years after psilocybin trial – Ohio State News

Study paper: Five-year outcomes of psilocybin-assisted therapy for Major Depressive Disorder

Convergent evolution of psilocybin

A new study shows that different types of mushrooms use completely different methods to produce the psychoactive substance psilocybin

Study Paper: Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms

Australia-first

Australia-first trial shows promising results for psychedelic-assisted therapy in palliative care

Study Paper: Psilocybin-assisted psychotherapy for depression and anxiety associated with life threatening illness: A phase 2b randomized controlled trial

First steps toward psilocybin access in Germany 

Compassionate Use Program for psilocybin possible for the first time in Germany